Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863289 | 0.84 | MTNR1A (0.52) | MTNR1AMTNR1BKDM4EALDH1A1HTT | |
| SCHEMBL7469745 | 0.84 | POLQ (0.52) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL29209917 | 0.84 | MTNR1A (0.44) | POLQMAOBMAOALMNAPOLB | |
| SCHEMBL871601 | 0.83 | POLQ (0.55) | POLQMAOBMAOAPOLBIDO1 | |
| SCHEMBL30474543 | 0.83 | POLQ (0.55) | POLQMAOBMAOAPOLBIDO1 | |
| SCHEMBL265536 | 0.81 | POLQ (0.59) | POLQMAOBMAOAPOLBIDO1 | |
| SCHEMBL31173765 | 0.81 | POLQ (0.59) | POLQMAOBMAOAPOLBIDO1 | |
| SCHEMBL3801344 | 0.81 | POLQ (0.56) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL19994734 | 0.80 | MTNR1A (0.51) | MAOBMTNR1AMTNR1BALDH1A1TDP1 | |
| SCHEMBL27856309 | 0.79 | POLQ (0.54) | POLQMTNR1AMTNR1BIDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482276-A | Heterocyclic compounds and their use | TAKEDA PHARMACEUTICAL | 2012-05-30 | — | — | CN | disclosed |