Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298105 | 0.79 | NFE2L2 (0.58) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1385780 | 0.76 | NFE2L2 (0.50) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27644490 | 0.76 | DGAT1 (0.44) | BACE1 | |
| SCHEMBL132365 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29824365 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9996395 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28821844 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4905475 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1384058 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL319771 | 0.75 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471294-A | Chiral cyclic beta-amino aryl butyric acid derivative, preparation method thereof and method for preparing chiral beta-amino aryl butyric acid derivative by using same | UNITRIS BIOPHARMA CO LTD | 2012-05-23 | — | — | CN | disclosed |