Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.30 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789384 | 0.91 | PDK2 (0.32) | PDK2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2814756 | 0.87 | PDK2 (0.35) | PDK2NR1H2RXRANR1H3 | |
| SCHEMBL2786649 | 0.87 | ABCG2 (0.31) | ABCG2 | |
| SCHEMBL782219 | 0.85 | ABCG2 (0.37) | ABCG2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2788005 | 0.84 | PDK2 (0.32) | PDK2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2788024 | 0.83 | CDK1 (0.40) | PDK2 | |
| SCHEMBL802092 | 0.80 | ABCG2 (0.35) | ABCG2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL783165 | 0.80 | MEN1 (0.32) | PDK2RXRALMNAGAAALOX15 | |
| SCHEMBL10052687 | 0.77 | MEN1 (0.34) | RXRALMNA | |
| SCHEMBL802490 | 0.77 | MEN1 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136109-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |