Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687298 | 0.89 | RXRA (0.40) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL802490 | 0.87 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL802740 | 0.86 | ALDH1A1 (0.33) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL783561 | 0.86 | ALDH1A1 (0.33) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL783126 | 0.85 | RXRA (0.32) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL802738 | 0.85 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL783165 | 0.84 | MEN1 (0.32) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL782089 | 0.84 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL802996 | 0.84 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL802706 | 0.84 | MEN1 (0.31) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-9231220-B2 | Substituted tetraarylbenzenes | MERCK PATENT GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-9231220-B2 | Substituted tetraarylbenzenes | MERCK PATENT GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-20150057445-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-20150057445-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-8906893-B2 | Substituted tetraarylbenzenes | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| US-8906893-B2 | Substituted tetraarylbenzenes | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| WO-2012079678-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | MEN1 2568/4885KMT2A 1267/4885MAPT 1547/4885 |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | MEN1 2568/4885KMT2A 1267/4885MAPT 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.