Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789384 | 0.90 | PDK2 (0.32) | PDK2 | |
| SCHEMBL783043 | 0.84 | CDK1 (0.52) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL2787393 | 0.83 | ABCG2 (0.34) | PDK2 | |
| SCHEMBL2814756 | 0.81 | PDK2 (0.35) | PDK2 | |
| SCHEMBL2788005 | 0.80 | PDK2 (0.32) | PDK2TSPO | |
| SCHEMBL2787224 | 0.80 | TSPO (0.46) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL782826 | 0.76 | DNMT1 (0.40) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL2786649 | 0.73 | ABCG2 (0.31) | — | |
| SCHEMBL782312 | 0.73 | CCNB2 (0.40) | CDK1CCNB2CCNB1GSK3BCCNB3 | |
| SCHEMBL782285 | 0.72 | PGR (0.35) | CDK1CCNB2CCNB1GSK3BCCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136109-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |