⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996586 | 0.80 | SLC7A5 (0.44) | — | |
| SCHEMBL11139682 | 0.78 | GABRP (0.33) | — | |
| SCHEMBL1412968 | 0.78 | — | — | |
| SCHEMBL7406641 | 0.77 | SLC7A5 (0.52) | — | |
| SCHEMBL8744775 | 0.76 | — | — | |
| SCHEMBL6852635 | 0.76 | — | — | |
| SCHEMBL3922773 | 0.76 | — | — | |
| SCHEMBL12910702 | 0.76 | — | — | |
| SCHEMBL16029664 | 0.76 | — | — | |
| SCHEMBL5699655 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102436-A | Microcrystalline diketopiperazine compositions and methods | MANNKIND CORP | 2015-11-25 | — | — | CN | disclosed |
| CN-102458371-B | Diketopiperazine microparticles with defined isomer content | MANNKIND CORP. (US) | 2015-08-05 | — | — | CN | disclosed |
| CN-104721825-A | Diketopiperazine Microparticles With Defined Specific Surface Areas | MANNKIND CORP | 2015-06-24 | — | — | CN | disclosed |
| CN-102647979-B | Diketopiperazine particles with defined specific surface area | MANNKIND CORP | 2015-03-04 | — | — | CN | disclosed |
| CN-103732220-A | High capacity diketopiperazine microparticles | MANNKIND CORP | 2014-04-16 | — | — | CN | disclosed |
| CN-102647979-A | Diketopiperazine particles with defined specific surface area | MANNKIND CORP | 2012-08-22 | — | — | CN | disclosed |
| CN-102458371-A | Diketopiperazine microparticles with defined isomer content | MANNKIND CORP | 2012-05-16 | — | — | CN | disclosed |