⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029664 | 1.00 | — | — | |
| SCHEMBL6852635 | 0.78 | — | — | |
| SCHEMBL8744775 | 0.78 | — | — | |
| SCHEMBL12910702 | 0.78 | — | — | |
| SCHEMBL3922773 | 0.78 | — | — | |
| SCHEMBL195750 | 0.77 | — | — | |
| SCHEMBL24925542 | 0.76 | ALDH1A1 (0.53) | — | |
| SCHEMBL1986431 | 0.76 | GABRP (0.54) | — | |
| SCHEMBL27761365 | 0.76 | LTA4H (0.47) | — | |
| SCHEMBL27874170 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872539-B2 | Analytical system based upon spore germination | ROTMAN M BORIS (US) | 2005-03-29 | — | — | US | claimed |
| US-20030008337-A1 | Analytical system based upon spore germination | ROTMAN M BORIS (US) | 2003-01-09 | — | — | US | claimed |
| US-6228574-B1 | RAPID DETECTION BY MIXING TEST SAMPLE WITH MICROBIAL SPORES AND GERMINOGENIC SOURCE, INCUBATING TO ALLOW ACTIVATION OF SPORES AND ENZYMATIC CONVERSION OF SOURCE TO A GERMINANT AND FOR SPORE GERMINATION, THEN DETECTING GERMINATION | ROTMAN M BORIS (US) | 2001-05-08 | — | — | US | claimed |
| EP-1131462-B1 | ANALYTICAL SYSTEM BASED UPON SPORE GERMINATION | ROTMAN M BORIS (US) | 2006-07-19 | — | — | EP | disclosed |
| US-6872539-B2 | Analytical system based upon spore germination | ROTMAN M BORIS (US) | 2005-03-29 | — | — | US | disclosed |
| US-6596496-B1 | Detecting preferential particle in sample; obtain spore sample, incubate with germination agent, monitor sample for spore generation | ROTMAN M BORIS (US) | 2003-07-22 | — | — | US | disclosed |
| US-20030008337-A1 | Analytical system based upon spore germination | ROTMAN M BORIS (US) | 2003-01-09 | — | — | US | disclosed |
| EP-1131462-A1 | ANALYTICAL SYSTEM BASED UPON SPORE GERMINATION | Rotman, M. Boris (US) | 2001-09-12 | — | — | EP | disclosed |
| US-6228574-B1 | RAPID DETECTION BY MIXING TEST SAMPLE WITH MICROBIAL SPORES AND GERMINOGENIC SOURCE, INCUBATING TO ALLOW ACTIVATION OF SPORES AND ENZYMATIC CONVERSION OF SOURCE TO A GERMINANT AND FOR SPORE GERMINATION, THEN DETECTING GERMINATION | ROTMAN M BORIS (US) | 2001-05-08 | — | — | US | disclosed |
| WO-2000029610-A1 | ANALYTICAL SYSTEM BASED UPON SPORE GERMINATION | ROTMAN M BORIS (US) | 2000-05-25 | — | — | WO | disclosed |