Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890628 | 0.98 | MEN1 (0.36) | MEN1KMT2AGPR84USP2LMNA | |
| SCHEMBL27485917 | 0.97 | MEN1 (0.36) | MEN1KMT2AGPR84USP2LMNA | |
| SCHEMBL30400548 | 0.90 | GPR84 (0.38) | MEN1KMT2AGPR84USP2LMNA | |
| SCHEMBL1487458 | 0.84 | CYP3A4 (0.44) | MEN1KMT2AUSP2LMNACA2 | |
| Lithium Ion SCHEMBL21541943 | 0.83 | CA1 (0.39) | MEN1KMT2ACA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6739022 | 0.81 | CA1 (0.40) | MEN1KMT2ACA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2869215 | 0.81 | INPPL1 (0.46) | MEN1KMT2AUSP2LMNACA2 | |
| SCHEMBL5085354 | 0.81 | MEN1 (0.39) | MEN1KMT2AGPR84USP2LMNA | |
| SCHEMBL28468987 | 0.80 | CA1 (0.39) | MEN1KMT2ACA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28946510 | 0.80 | INPPL1 (0.44) | MEN1KMT2AUSP2LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712186-A | Multilayer blow-molded container, and process for production thereof | PRIME POLYMER CO LTD | 2012-10-03 | — | — | CN | disclosed |