⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509074 | 0.70 | DPP4 (0.36) | — | |
| SCHEMBL15954726 | 0.69 | — | — | |
| SCHEMBL1382152 | 0.69 | — | — | |
| SCHEMBL28299258 | 0.69 | — | — | |
| SCHEMBL5698541 | 0.68 | — | — | |
| Dimethyl Sulfoxide SCHEMBL28460386 | 0.67 | MEN1 (0.35) | — | |
| SCHEMBL5570701 | 0.67 | KDM4E (0.35) | — | |
| SCHEMBL28199154 | 0.66 | — | — | |
| SCHEMBL2879092 | 0.65 | PDE2A (0.32) | — | |
| SCHEMBL196119 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516860-B | Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors | NOVARTIS AG | 2012-06-27 | — | — | CN | claimed |
| CN-101516860-A | Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | claimed |
| CN-101516860-B | Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors | NOVARTIS AG | 2012-06-27 | — | — | CN | disclosed |
| CN-101516860-A | Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | disclosed |