Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753927 | 0.83 | S1PR1 (0.38) | PNMTTAAR1MEN1KMT2AS1PR1 | |
| SCHEMBL12841593 | 0.81 | SKP2 (0.46) | PNMTTAAR1SIGMAR1CYP1A2MEN1 | |
| SCHEMBL1612361 | 0.80 | SKP2 (0.39) | CYP1A2ALDH1A1MAPTCYP2C19SKP2 | |
| SCHEMBL3565937 | 0.80 | PNMT (0.61) | PNMTTAAR1SIGMAR1CYP1A2MEN1 | |
| SCHEMBL29434783 | 0.79 | ALDH1A1 (0.47) | PNMTTAAR1ALDH1A1TP53MAPT | |
| SCHEMBL12333663 | 0.79 | ALDH1A1 (0.47) | PNMTTAAR1ALDH1A1TP53MAPT | |
| SCHEMBL7458179 | 0.79 | PNMT (0.41) | PNMTTAAR1SIGMAR1CYP1A2MEN1 | |
| SCHEMBL3840980 | 0.79 | TAAR1 (0.67) | PNMTTAAR1SIGMAR1CYP1A2ALDH1A1 | |
| SCHEMBL86433 | 0.76 | SKP2 (0.42) | PNMTTAAR1SIGMAR1CYP1A2MEN1 | |
| SCHEMBL81132 | 0.76 | IGF1R (0.44) | PNMTTAAR1ALDH1A1TP53S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741227-A | Aryl benzylamine compounds | NOVARTIS AG | 2012-10-17 | — | — | CN | claimed |
| CN-102741227-A | Aryl benzylamine compounds | NOVARTIS AG | 2012-10-17 | — | — | CN | disclosed |