Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 4/20 | 0.57 |
| ▸ | MIF | P14174 | 8/20 | 0.50 |
| ▸ | CD74 | P04233 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69876 | 0.85 | ESRRA (0.62) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL3477570 | 0.84 | CA1 (0.57) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL11902351 | 0.84 | CA1 (0.57) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL30398926 | 0.84 | ESRRA (0.56) | ESRRAMIFCD74CA1CA2 | |
| SCHEMBL2330243 | 0.84 | CA1 (0.57) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL28801446 | 0.84 | ESRRA (0.60) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL1749529 | 0.83 | OGT (0.53) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL27911606 | 0.83 | CA1 (0.56) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL4708257 | 0.82 | MAOA (0.49) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL28797039 | 0.80 | HSD17B1 (0.56) | ESRRAMAOAMAOBHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753562-B | As the mannose derivative of bacterial adhesion antagonist | UNIVERSITAT BASEL (CH) | 2015-11-25 | — | — | CN | disclosed |
| CN-102753562-A | Mannose derivatives as antagonists of bacterial adhesion | UNIV BASEL | 2012-10-24 | — | — | CN | disclosed |