Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783570 | 0.86 | DHODH (0.63) | DHODHRAB9ACYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL1826746 | 0.82 | RAB9A (0.73) | DHODHRAB9ACYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL2787428 | 0.82 | MAPT (0.44) | DHODHRAB9ACYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL2784670 | 0.82 | IL2 (0.44) | CYP1A2HTR2AKDRTEKIL2 | |
| SCHEMBL2785720 | 0.82 | KDR (0.38) | RAB9ACYP3A4CYP2C9SMN1; SMN2NPSR1 | |
| SCHEMBL2785179 | 0.82 | MAPT (0.44) | RAB9ASMN1; SMN2NPSR1NPC1LMNA | |
| SCHEMBL2784731 | 0.81 | KDM4E (0.40) | DHODHRAB9ACYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL2785065 | 0.80 | TRPV1 (0.45) | NPSR1HTR2ATRPV1MAPT | |
| SCHEMBL2784884 | 0.79 | IL2 (0.42) | PIM1KDRFLT3KITPDGFRB | |
| SCHEMBL2785601 | 0.78 | RAB9A (0.45) | RAB9ACYP3A4CYP2C9SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651232-B1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2010-12-22 | — | — | EP | claimed |