SCHEMBL2787808

SCHEMBL2787808

Cn1cccc1C=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
KMT2A Q03164 6/20 0.45
MEN1 O00255 4/20 0.45
ALDH1A1 P00352 6/20 0.43
MAPT P10636 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
GAA P10253 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
RELA Q04206 2/20 0.43
USP2 O75604 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
TLR9 Q9NR96 1/20 0.43
CHAT P28329 2/20 0.42
MAOB P27338 3/20 0.41
KDM4E B2RXH2 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787807 1.00 TRIM24 (0.52) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL12086582 1.00 TRIM24 (0.52) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL15871031 0.87 TRIM24 (0.65) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL8618552 0.82 TRIM24 (0.47) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL8618557 0.82 TRIM24 (0.47) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL8445931 0.81 TRIM24 (0.54) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL2399255 0.81 EP300 (0.48) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL2399252 0.81 EP300 (0.48) TRIM24TRIM33KMT2AMEN1ALDH1A1
SCHEMBL19076194 0.80 TRPA1 (0.56) KMT2AALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL2400973 0.79 EP300 (0.47) TRIM24TRIM33KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101809051-B Functionalized polymers, articles prepared therefrom, and methods of making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-29 CN disclosed
EP-2495268-B1 Compositions and articles DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-01 EP disclosed
US-9000099-B2 Functionalized polymers, articles prepared therefrom, and methods for making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-07 US disclosed
EP-2170970-B1 FUNCTIONALIZED POLYMERS AND ARTICLES PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2014-09-03 EP disclosed
EP-2495268-A1 Compositions and articles Dow Global Technologies LLC (US) 2012-09-05 EP disclosed
CN-101809051-A Functionalized polymers, articles prepared therefrom, and methods of making the same DOW GLOBAL TECHNOLOGIES INC 2010-08-18 CN disclosed
US-20100168343-A1 FUNCTIONALIZED POLYMERS, ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2010-07-01 US disclosed
EP-2170970-A1 FUNCTIONALIZED POLYMERS, ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME Dow Global Technologies Inc. (US) 2010-04-07 EP disclosed
WO-2009012113-A1 FUNCTIONALIZED POLYMERS, ARTICLES PREPARED THEREFROM, AND METHODS FOR MAKING THE SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2009-01-22 WO disclosed