Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618552 | 1.00 | TRIM24 (0.47) | TRIM24TRIM33MAOAMAOBRAB9A | |
| SCHEMBL12086582 | 0.82 | TRIM24 (0.52) | TRIM24TRIM33MAOAMAOBRAB9A | |
| SCHEMBL2787807 | 0.82 | TRIM24 (0.52) | TRIM24TRIM33MAOAMAOBRAB9A | |
| SCHEMBL2787808 | 0.82 | TRIM24 (0.52) | TRIM24TRIM33MAOAMAOBRAB9A | |
| SCHEMBL15871031 | 0.82 | TRIM24 (0.65) | TRIM24TRIM33RAB9AALDH1A1KDM4E | |
| SCHEMBL19076194 | 0.79 | TRPA1 (0.56) | RAB9AALDH1A1CYP2C19KDM4EHPGD | |
| SCHEMBL2399252 | 0.76 | EP300 (0.48) | TRIM24TRIM33RAB9AALDH1A1KDM4E | |
| SCHEMBL2399255 | 0.76 | EP300 (0.48) | TRIM24TRIM33RAB9AALDH1A1KDM4E | |
| SCHEMBL2400973 | 0.75 | EP300 (0.47) | TRIM24TRIM33RAB9AALDH1A1KDM4E | |
| SCHEMBL2400966 | 0.75 | EP300 (0.47) | TRIM24TRIM33RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674636-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-05-20 | — | — | EP | disclosed |
| EP-0674636-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014804-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |