Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 3/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 7/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13279099 | 0.89 | ESR1 (0.58) | PSMB1PSMB5PSMB2LTA4HESR1 | |
| SCHEMBL27895118 | 0.80 | PDK2 (0.48) | ESR1ESR2 | |
| SCHEMBL27878251 | 0.79 | PDK2 (0.49) | LTA4HESR1ESR2 | |
| SCHEMBL27878248 | 0.77 | CA12 (0.48) | LTA4H | |
| SCHEMBL27878343 | 0.76 | PDK2 (0.47) | LTA4HESR1ESR2 | |
| SCHEMBL27878250 | 0.73 | CA12 (0.42) | ESR1ESR2 | |
| SCHEMBL27895119 | 0.72 | TDP1 (0.50) | ESR1ESR2 | |
| SCHEMBL699174 | 0.72 | ESR1 (0.76) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL1359959 | 0.72 | ESR1 (0.76) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL3951411 | 0.72 | LTA4H (0.83) | PSMB1PSMB5PSMB2LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102727470-A | Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer | UNIV BEIJING | 2012-10-17 | — | — | CN | disclosed |