Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951065 | 0.88 | NPC1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27895118 | 0.85 | PDK2 (0.48) | — | |
| SCHEMBL27878251 | 0.84 | PDK2 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27878343 | 0.81 | PDK2 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27895117 | 0.78 | PDK2 (0.43) | — | |
| SCHEMBL27878250 | 0.77 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27878253 | 0.77 | PSMB1 (0.56) | LTA4H | |
| SCHEMBL17445872 | 0.76 | PDK2 (0.41) | — | |
| SCHEMBL6756884 | 0.76 | ESR1 (0.49) | CA12CA2NPC1RAB9AHPGD | |
| SCHEMBL16902905 | 0.76 | LMNA (0.47) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102727470-A | Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer | UNIV BEIJING | 2012-10-17 | — | — | CN | disclosed |