Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.36 |
| ▸ | CDK9 | P50750 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980058 | 0.89 | TLR9 (0.54) | TLR9TLR7TLR8PLATABCB1 | |
| Tert-Butyl Formate SCHEMBL27878459 | 0.81 | PLAT (0.37) | TLR9TLR7TLR8PLAT | |
| SCHEMBL1980796 | 0.76 | TLR7 (0.53) | TLR7TLR8ABCB1CCNT1CDK9 | |
| SCHEMBL27878434 | 0.75 | ABCB1 (0.46) | TLR9TLR7TLR8ABCB1 | |
| Tert-Butyl Formate SCHEMBL28309477 | 0.75 | TLR9 (0.45) | TLR9TLR7TLR8PLAT | |
| Tert-Butyl Formate SCHEMBL27862135 | 0.74 | PLAT (0.38) | TLR9TLR7TLR8PLAT | |
| SCHEMBL29123374 | 0.69 | TLR9 (0.58) | TLR9TLR7TLR8PLATCCNT1 | |
| Tert-Butyl Formate SCHEMBL28298594 | 0.68 | HTR2C (0.73) | — | |
| Tert-Butyl Formate SCHEMBL28108127 | 0.68 | HTR2C (0.44) | TLR9TLR7 | |
| SCHEMBL23010839 | 0.67 | TLR9 (0.47) | TLR9TLR7TLR8CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753524-B | Bicyclic derivatives useful as inhibitors of dpp-1 | ANSSEN PHARMACEUTICA NV | 2014-11-05 | — | — | CN | disclosed |
| CN-102753524-A | Bicyclic derivatives useful as inhibitors of dpp-1 | ANSSEN PHARMACEUTICA NV | 2012-10-24 | — | — | CN | disclosed |