Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261970 | 0.89 | HPGDS (0.52) | TLR9TLR7TLR8HPGDSKMT2A | |
| Bromide SCHEMBL2984287 | 0.88 | HPGDS (0.51) | TLR9TLR7TLR8HPGDSKMT2A | |
| Tert-Butyl Formate SCHEMBL28787887 | 0.83 | HPGDS (0.60) | HPGDSKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL30720990 | 0.75 | HTT (0.50) | TLR7TLR8KMT2AMEN1ALDH1A1 | |
| SCHEMBL20116206 | 0.75 | HTT (0.50) | TLR7TLR8KMT2AMEN1ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27878435 | 0.75 | TLR9 (0.45) | TLR9TLR7TLR8PLAT | |
| SCHEMBL5074842 | 0.75 | MAPT (0.45) | TLR9TLR7TLR8KMT2AMEN1 | |
| SCHEMBL4257174 | 0.74 | RAB9A (0.60) | HPGDSKMT2AMEN1ALDH1A1PKM | |
| Bromide SCHEMBL2972856 | 0.73 | NPC1 (0.62) | HPGDSKMT2AMEN1ALDH1A1PKM | |
| Tert-Butyl Formate SCHEMBL27768213 | 0.73 | AOC3 (0.46) | TLR9TLR7TLR8HPGDSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099898-A | compound and use thereof | 优曼尼蒂治疗公司 | 2019-08-06 | — | — | CN | disclosed |