Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 15/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980796 | 0.85 | TLR7 (0.53) | ABCB1TLR7TLR8PIK3CDPIK3CA | |
| SCHEMBL27878458 | 0.81 | HRH3 (0.42) | — | |
| SCHEMBL1980058 | 0.77 | TLR9 (0.54) | ABCB1TLR7TLR8TLR9 | |
| SCHEMBL27862133 | 0.75 | IDH1 (0.34) | TLR7TLR8TLR9 | |
| Tert-Butyl Formate SCHEMBL27878435 | 0.75 | TLR9 (0.45) | ABCB1TLR7TLR8TLR9 | |
| SCHEMBL28309475 | 0.74 | MEN1 (0.47) | — | |
| SCHEMBL1981327 | 0.72 | DPP4 (0.42) | ABCB1TLR7TLR8TLR9HTR2B | |
| SCHEMBL1981326 | 0.72 | DPP4 (0.42) | ABCB1TLR7TLR8TLR9HTR2B | |
| SCHEMBL1980557 | 0.72 | CTSS (0.41) | ABCB1TLR7TLR8TLR9 | |
| SCHEMBL1980560 | 0.72 | CTSS (0.41) | ABCB1TLR7TLR8TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753524-B | Bicyclic derivatives useful as inhibitors of dpp-1 | ANSSEN PHARMACEUTICA NV | 2014-11-05 | — | — | CN | disclosed |
| CN-102753524-A | Bicyclic derivatives useful as inhibitors of dpp-1 | ANSSEN PHARMACEUTICA NV | 2012-10-24 | — | — | CN | disclosed |