Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1981326 | 0.87 | DPP4 (0.42) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL1981327 | 0.87 | DPP4 (0.42) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL1980557 | 0.85 | CTSS (0.41) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL1980560 | 0.85 | CTSS (0.41) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL27878467 | 0.83 | TLR7 (0.37) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL1983514 | 0.74 | HTR2B (0.50) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL1983513 | 0.74 | HTR2B (0.50) | TLR7TLR8TLR9ALDH1A1NPSR1 | |
| SCHEMBL1980796 | 0.73 | TLR7 (0.53) | TLR7TLR8ABCB1PDE4BKDM4E | |
| SCHEMBL1982922 | 0.73 | HTR2B (0.46) | TLR7TLR8TLR9ALDH1A1HSD17B10 | |
| SCHEMBL1982924 | 0.73 | HTR2B (0.46) | TLR7TLR8TLR9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753524-B | Bicyclic derivatives useful as inhibitors of dpp-1 | ANSSEN PHARMACEUTICA NV | 2014-11-05 | — | — | CN | disclosed |
| CN-102753524-A | Bicyclic derivatives useful as inhibitors of dpp-1 | ANSSEN PHARMACEUTICA NV | 2012-10-24 | — | — | CN | disclosed |