Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705929 | 0.81 | EGLN1 (0.62) | PDE3BPDE3AEGLN1 | |
| SCHEMBL27876652 | 0.77 | EGLN1 (0.49) | EGLN1 | |
| SCHEMBL5090728 | 0.76 | PDE3B (0.42) | PDE3BPDE3AEGLN1ALDH1A1MAPT | |
| SCHEMBL6565239 | 0.73 | PDE3B (0.49) | PDE3BPDE3AEGLN1ALDH1A1HPGD | |
| SCHEMBL22288463 | 0.71 | PDE3B (0.44) | PDE3BPDE3AEGLN1ALDH1A1MAPT | |
| SCHEMBL6566125 | 0.68 | EGLN1 (0.52) | EGLN1 | |
| SCHEMBL13310734 | 0.68 | PDE3B (0.46) | PDE3BPDE3AEGLN1ALDH1A1MAPT | |
| SCHEMBL6565865 | 0.68 | EGLN1 (0.57) | EGLN1ALDH1A1HPGDKDM4E | |
| SCHEMBL5285305 | 0.67 | GRK2 (0.55) | ALDH1A1MAPTTSHRTP53KDM4E | |
| SCHEMBL1509148 | 0.67 | EGLN1 (0.50) | PDE3BPDE3AEGLN1PDE2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102552263-A | Methods of increasing endogenous erythropoietin EPO | FIBROGEN INC | 2012-07-11 | — | — | CN | disclosed |