Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565239 | 0.82 | PDE3B (0.49) | PDE3BPDE3AALDH1A1EGLN1KMT2A | |
| SCHEMBL5090728 | 0.77 | PDE3B (0.42) | PDE3BPDE3AALDH1A1EGLN1KMT2A | |
| SCHEMBL705929 | 0.77 | EGLN1 (0.62) | PDE3BPDE3AEGLN1 | |
| SCHEMBL27878745 | 0.71 | PDE3B (0.46) | PDE3BPDE3AALDH1A1EGLN1KMT2A | |
| SCHEMBL6535849 | 0.71 | KDM4E (0.51) | PDE3BPDE3AALDH1A1KDM4EGLA | |
| SCHEMBL4658383 | 0.70 | KMO (0.39) | CA2 | |
| SCHEMBL27592805 | 0.70 | PDE3B (0.45) | PDE3BPDE3AALDH1A1KMT2APARP10 | |
| SCHEMBL6567169 | 0.68 | ALDH1A1 (0.52) | PDE3BPDE3AALDH1A1KMT2AKDM4E | |
| SCHEMBL6565253 | 0.67 | TDP1 (0.43) | EGLN1KMT2ASMN1; SMN2HDAC8TP53 | |
| SCHEMBL8629707 | 0.66 | MCL1 (0.51) | PDE3BPDE3AALDH1A1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11969417-B2 | Topical formulation for use in alopecia | TOMORROWLABS GMBH (AT) | 2024-04-30 | — | — | US | disclosed |
| EP-3917525-B1 | NEW TOPICAL FORMULATION FOR USE IN ALOPECIA | TOMORROWLABS GMBH (AT) | 2024-02-28 | — | — | EP | disclosed |
| WO-2021259471-A1 | DERMAL FILLER WITH HIF-1α ACTIVITY MODULATORS | THOR DOMINIK (AT) | 2021-12-30 | — | — | WO | disclosed |
| EP-3917525-A1 | NEW TOPICAL FORMULATION FOR USE IN ALOPECIA | Tomorrowlabs GmbH (AT) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020157064-A1 | NEW TOPICAL FORMULATION FOR USE IN ALOPECIA | TOMORROWLABS GMBH (AT) | 2020-08-06 | — | — | WO | disclosed |