Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796332 | 0.84 | SCD (0.51) | SCDGRM2PKMMARS1ADRA1D | |
| SCHEMBL27878948 | 0.81 | SCD (0.48) | SCDPKMGAAGRIN1GRIN2B | |
| SCHEMBL14480159 | 0.73 | SCD (0.62) | SCDGAA | |
| SCHEMBL27878887 | 0.73 | SCD (0.52) | SCDSMN1; SMN2 | |
| SCHEMBL27878888 | 0.72 | SCD (0.51) | SCD | |
| SCHEMBL12717805 | 0.71 | SCD (0.62) | SCDGAA | |
| SCHEMBL27777529 | 0.71 | SCD (0.47) | SCDPKMSMN1; SMN2P2RX7 | |
| SCHEMBL245376 | 0.70 | SCD (0.77) | SCDSMN1; SMN2 | |
| SCHEMBL27878893 | 0.70 | SCD (0.44) | SCDPKMGAAJAK2JAK1 | |
| SCHEMBL1576950 | 0.69 | SCD (0.61) | SCDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574841-A | Pyrazole derivatives which modulate stearoyl-coa desaturase | NOVARTIS AG | 2012-07-11 | — | — | CN | disclosed |