Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14480232 | 0.75 | SCD (0.54) | SCDGAA | |
| SCHEMBL27878950 | 0.70 | SCD (0.51) | SCDPKMSMN1; SMN2GAAJAK2 | |
| SCHEMBL28796332 | 0.69 | SCD (0.51) | SCDALDH1A1PKMHPGDSMN1; SMN2 | |
| SCHEMBL27777529 | 0.66 | SCD (0.47) | SCDALDH1A1PKMSMN1; SMN2P2RX7 | |
| SCHEMBL14480159 | 0.66 | SCD (0.62) | SCDGAA | |
| SCHEMBL12717805 | 0.63 | SCD (0.62) | SCDGAA | |
| Urea SCHEMBL28754568 | 0.62 | GRM2 (0.60) | GAA | |
| SCHEMBL27878948 | 0.61 | SCD (0.48) | SCDALDH1A1PKMHPGDSMN1; SMN2 | |
| SCHEMBL27878887 | 0.60 | SCD (0.52) | SCDALDH1A1SMN1; SMN2 | |
| SCHEMBL14480143 | 0.59 | ALDH1A1 (0.61) | ALDH1A1PKMP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574841-A | Pyrazole derivatives which modulate stearoyl-coa desaturase | NOVARTIS AG | 2012-07-11 | — | — | CN | disclosed |