Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902986 | 0.87 | CYP19A1 (0.50) | MAOBMEN1KMT2AMAPTNPC1 | |
| SCHEMBL31056274 | 0.86 | ERN1 (0.49) | MAOBMEN1KMT2AMAPTNPC1 | |
| SCHEMBL4585380 | 0.82 | NPC1 (0.53) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8077523 | 0.82 | CYP19A1 (0.55) | MEN1KMT2AMAPTCYP19A1PIN1 | |
| SCHEMBL6926436 | 0.78 | MAPT (0.62) | MAOBMEN1KMT2AMAPTNPC1 | |
| SCHEMBL27896296 | 0.77 | NPC1 (0.45) | MEN1KMT2ANPC1RAB9APIN1 | |
| SCHEMBL4891360 | 0.77 | MAPT (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9388459 | 0.76 | MEN1 (0.58) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9148579 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4883605 | 0.76 | BACE1 (0.53) | MAOBMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731488-A | Benzimidazole derivatives, preparation method thereof, pharmaceutical composition thereof and application thereof | INST MATERIA MEDICA CAMS | 2012-10-17 | — | — | CN | disclosed |
| CN-102621830-A | Electrophotographic photoconductor and image forming apparatus using the same | SHARP KK | 2012-08-01 | — | — | CN | disclosed |