Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879445 | 0.86 | MAOB (0.45) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31091843 | 0.82 | PTGES (0.48) | GAAMAPTHPGDMEN1NPC1 | |
| SCHEMBL4585380 | 0.81 | NPC1 (0.53) | ERN1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL11685931 | 0.81 | MAPT (0.68) | ERN1GAAMAPTHPGDMEN1 | |
| SCHEMBL11075503 | 0.80 | HTR1A (0.53) | GAAMAPTMEN1KMT2AHTR1A | |
| SCHEMBL4055189 | 0.79 | GAA (0.51) | ERN1GAAMAPTHPGDMAOA | |
| SCHEMBL16378450 | 0.78 | MAPT (0.39) | GAAMAPTHPGDMEN1NPC1 | |
| SCHEMBL17746516 | 0.78 | MAPT (0.39) | GAAMAPTHPGDMEN1NPC1 | |
| SCHEMBL21596262 | 0.76 | ALDH1A1 (0.55) | ERN1GAAMAPTHPGDMEN1 | |
| SCHEMBL27896296 | 0.76 | NPC1 (0.45) | MEN1NPC1RAB9AKMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |