Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799623 | 0.91 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27897376 | 0.89 | BCHE (0.47) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27880492 | 0.84 | GPR6 (0.46) | ALDH1A1FAAHMAPTTSHRGAA | |
| SCHEMBL27897396 | 0.84 | MEN1 (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2221996 | 0.83 | MEN1 (0.47) | PRKAA2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL27897410 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27897412 | 0.83 | GLA (0.41) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27897415 | 0.82 | GPR6 (0.43) | PRKAA2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL27897418 | 0.79 | HTR3E (0.47) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27897394 | 0.78 | MEN1 (0.45) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102802627-A | Voltage-gated sodium channel blockers | GLAXO GROUP LTD | 2012-11-28 | — | — | CN | claimed |
| CN-102802627-A | Voltage-gated sodium channel blockers | GLAXO GROUP LTD | 2012-11-28 | — | — | CN | disclosed |