Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | GAK | O14976 | 6/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443046 | 0.90 | GAK (0.59) | GAKERN1KITPDE10AALDH1A1 | |
| SCHEMBL27882019 | 0.89 | PIK3CA (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGGAK | |
| SCHEMBL27865681 | 0.87 | MTOR (0.49) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL1442375 | 0.86 | CNR2 (0.66) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL1442664 | 0.84 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL3091537 | 0.84 | PIK3CA (0.55) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL10179693 | 0.84 | ALDH1A1 (0.51) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL12811769 | 0.84 | TNIK (0.55) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL27882012 | 0.84 | MEN1 (0.47) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL1443292 | 0.84 | CNR2 (0.53) | PIK3CDPIK3CAPIK3CBMTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |