Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12811769 | 0.92 | TNIK (0.55) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL27865823 | 0.90 | HRH4 (0.49) | NPC1RAB9ACNR2HRH4ALDH1A1 | |
| SCHEMBL1443214 | 0.88 | ALDH1A1 (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1442380 | 0.88 | TNIK (0.50) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL27882073 | 0.88 | AR (0.52) | MEN1KMT2ATNIKALDH1A1LMNA | |
| SCHEMBL12811770 | 0.86 | NPC1 (0.56) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL1442713 | 0.86 | ALDH1A1 (0.61) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL12812382 | 0.86 | CNR2 (0.54) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL12812388 | 0.84 | PDE10A (0.44) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27882034 | 0.84 | PIK3CD (0.49) | NPC1RAB9ACNR2ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |