Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | MTOR | P42345 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442175 | 0.92 | PIK3CA (0.50) | PIK3CAMETPDGFRBPDGFRANPC1 | |
| SCHEMBL27882073 | 0.90 | AR (0.52) | PIK3CAMEN1KMT2APIK3CBMTOR | |
| SCHEMBL1442139 | 0.89 | ALDH1A1 (0.47) | PIK3CAPDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL1441904 | 0.88 | MAPT (0.49) | PIK3CAMETNPC1RAB9AMAOB | |
| SCHEMBL12812447 | 0.87 | PTPN11 (0.46) | PIK3CAMETNPC1RAB9AMEN1 | |
| SCHEMBL27865823 | 0.87 | HRH4 (0.49) | PIK3CAMETNPC1RAB9AMAOB | |
| SCHEMBL1443038 | 0.85 | PIK3CA (0.55) | PIK3CANPC1RAB9AMEN1KMT2A | |
| SCHEMBL12811790 | 0.84 | PIK3CA (0.52) | PIK3CAMETNPC1RAB9AMEN1 | |
| SCHEMBL1442090 | 0.84 | PDGFRB (0.51) | PIK3CAMETPDGFRBPDGFRANPC1 | |
| SCHEMBL27865822 | 0.84 | PIK3CA (0.48) | PIK3CAMETPDGFRBPDGFRANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |