Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | GAK | O14976 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442090 | 0.91 | PDGFRB (0.51) | PIK3CAGAKPDGFRBPDGFRAMET | |
| SCHEMBL1441906 | 0.89 | GAK (0.56) | PIK3CAGAKPDGFRBPDGFRAMET | |
| SCHEMBL27865681 | 0.89 | MTOR (0.49) | PIK3CAGAKALDH1A1NPC1RAB9A | |
| SCHEMBL27882019 | 0.86 | PIK3CA (0.48) | PIK3CAGAKPDGFRBPDGFRAMET | |
| SCHEMBL1442748 | 0.85 | PIK3CA (0.53) | PIK3CAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL27865701 | 0.84 | MAP4K1 (0.52) | PIK3CAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL27882148 | 0.84 | PIK3CA (0.51) | PIK3CAGAKPDGFRBPDGFRAMET | |
| SCHEMBL1442175 | 0.83 | PIK3CA (0.50) | PIK3CAGAKPDGFRBPDGFRAMET | |
| SCHEMBL1442235 | 0.83 | ALDH1A1 (0.47) | PIK3CAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL12811955 | 0.82 | GAK (0.42) | PIK3CAGAKMETMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |