Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295983 | 0.81 | MAPT (1.00) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL42323 | 0.81 | MAPT (1.00) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL10673342 | 0.81 | MAPT (1.00) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL820084 | 0.81 | MAPT (1.00) | MAPTMAOBMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL27758234 | 0.80 | MAPT (0.97) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL5441741 | 0.79 | MAPT (0.63) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL4185541 | 0.79 | MAPT (0.77) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL4185536 | 0.79 | MAPT (0.77) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL28977485 | 0.78 | MAPT (0.76) | MAPTMAOBMEN1KMT2ARAB9A | |
| SCHEMBL30449461 | 0.77 | MAOB (1.00) | MAPTMAOBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102838515-A | Cinnamoyl sulfonamide compound preparation and applications of cinnamoyl sulfonamide compounds in anti-tumor treatment drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2012-12-26 | — | — | CN | disclosed |