SCHEMBL42323

SCHEMBL42323

O=C(O)/C=C/c1ccccc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 1.00
MAOB P27338 1/20 0.73
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
RAB9A P51151 3/20 0.68
NPC1 O15118 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
NFKB1 P19838 2/20 0.68
KDM4E B2RXH2 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
ALDH1A1 P00352 8/20 0.61
LMNA P02545 3/20 0.61
ATM Q13315 2/20 0.61
HSP90AA1 P07900 1/20 0.61
BACE1 P56817 1/20 0.60
AR P10275 1/20 0.57
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA4 P22748 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820084 1.00 MAPT (1.00) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL10673342 1.00 MAPT (1.00) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL3295983 1.00 MAPT (1.00) MAPTMAOBMEN1KMT2ARAB9A
Hydrochloric Acid SCHEMBL27758234 0.98 MAPT (0.97) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL1232668 0.88 MAPT (0.79) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL1232666 0.88 MAPT (0.79) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL4185536 0.87 MAPT (0.77) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL4185541 0.87 MAPT (0.77) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL2184440 0.87 MAPT (0.77) MAPTMAOBMEN1KMT2ARAB9A
SCHEMBL28977485 0.86 MAPT (0.76) MAPTMAOBMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673529-A1 USE OF GELATIN IN A SUPPORT MATERIAL FOR EMBEDDED PRINTING Rousselot BV (BE) 2026-01-07 EP claimed
US-20250320333-A1 COMPOSITION FOR PREPARING POLYCAPROLACTONE SHAPE MEMORY MATERIAL, AND POLYCAPROLACTONE SHAPE MEMORY MATERIAL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2025-10-16 US claimed
US-20250271441-A1 APPLICATION OF CLICK CHEMISTRY FOR SIGNAL AMPLIFICATION IN IHC AND ISH ASSAYS VENTANA MED SYST INC (US) 2025-08-28 US claimed
US-12398419-B2 Automated RNA detection using labeled 2′-O-methyl RNA oligonucleotide probes and signal amplification systems VENTANA MEDICAL SYSTEMS, INC. (US) 2025-08-26 US claimed
CN-118086841-B TiSiNiYN coating for enhancing high-temperature wear resistance 纳狮新材料有限公司杭州分公司 2025-02-07 CN claimed
WO-2024218352-A1 USE OF GELATIN IN A SUPPORT MATERIAL FOR EMBEDDED PRINTING ROUSSELOT BV (BE) 2024-10-24 WO claimed
EP-4410863-A1 COMPOSITION FOR PREPARING POLYCAPROLACTONE SHAPE MEMORY MATERIAL, AND POLYCAPROLACTONE SHAPE MEMORY MATERIAL, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2024-08-07 EP claimed
CN-118086841-A TiSiNiYN coating for enhancing high-temperature wear resistance 纳狮新材料有限公司杭州分公司 2024-05-28 CN claimed
US-11780863-B2 Quinone methide analog signal amplification VENTANA MEDICAL SYSTEMS, INC. (US) 2023-10-10 US claimed
WO-2023027630-A9 A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-07-27 WO claimed
US-5807807-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US claimed
US-5707937-A AGRICULTURAL HERBICIDES, DESICCANTS, DEFOLIANTS, HARVESTING AIDS BASF AKTIENGESELLSCHAFT (DE) 1998-01-13 US claimed
CN-1162306-A Substitutecl phthalimido-cinnamic acid derivatives with herbicidal effect BASF AG (DE) 1997-10-15 CN claimed
EP-0379911-B1 N-PHENYL TETRAHYDROINDAZOLE DERIVATIVES BASF Aktiengesellschaft (DE) 1992-12-02 EP claimed
US-5035976-A Photoresists, improved shelf life HOECHST CELANESE CORPORATION (US) 1991-07-30 US claimed
EP-0155123-B1 YELLOW COLOR FORMERS FOR USE IN COLOR PHOTOTHERMOGRAPHIC SYSTEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-11 EP claimed
EP-0155123-A2 Yellow color formers for use in color photothermographic system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-09-18 EP claimed
US-4535056-A OXIDIZER, BIPHENOL REDUCING AGENT, AND CARBOXYLIC ACID MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-13 US claimed
US-4223948-A Process for the reduction of competitive oxidant consuming reactions in the solution mining of a mineral ATLANTIC RICHFIELD COMPANY (US) 1980-09-23 US claimed
US-4009033-A 1,2-QUINONE DIAZIDE SULFONATE AND NICOTINIC, PICRIC OR NITROCINNAMIC ACID INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1977-02-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250271441-A1 APPLICATION OF CLICK CHEMISTRY FOR SIGNAL AMPLIFICATION IN IHC AND ISH ASSAYS MKI67, TIE1, ALK MAPT 4162/4885MAOB 1677/4885MEN1 2491/4885
US-11780863-B2 Quinone methide analog signal amplification NQO2, SQOR, MRM1 MAPT 4787/4885MAOB 140/4885MEN1 2189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.