Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797216 | 0.86 | PHGDH (0.41) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27884356 | 0.85 | PPARG (0.43) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27884365 | 0.85 | ACLY (0.40) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27867729 | 0.84 | ACLY (0.38) | PPARGPPARDPPARAACLYKMT2A | |
| SCHEMBL28800052 | 0.84 | ACLY (0.43) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27867737 | 0.83 | SSTR5 (0.35) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27867735 | 0.83 | ACLY (0.42) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27884472 | 0.83 | PHGDH (0.39) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL27867759 | 0.82 | ACLY (0.38) | PPARGPPARDPPARAACLYPHGDH | |
| SCHEMBL12096651 | 0.81 | PPARG (0.61) | PPARGPPARDPPARAACLYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596906-A | Use of indole derivatives as NURR-1 activators as agents for the treatment of Parkinson's disease | FOURNIER LAB SA | 2012-07-18 | — | — | CN | disclosed |