SCHEMBL278874

SCHEMBL278874

C=CC(=O)OCCN(CCCC)C(=O)COc1ccc2sc3ccccc3c(=O)c2c1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTPN1 P18031 1/20 0.37
HSD17B10 Q99714 2/20 0.37
USP2 O75604 1/20 0.37
MAOA P21397 12/20 0.36
MAOB P27338 12/20 0.36
HPGD P15428 3/20 0.36
TSHR P16473 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278596 0.94 KDM4E (0.45) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL19185676 0.87 KDM4E (0.46) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL12256654 0.84 KDM4E (0.39) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL12795166 0.82 MAOA (0.50) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL22039253 0.81 KDM4E (0.46) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL13579134 0.81 MAOA (0.51) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL11994244 0.81 KDM4E (0.51) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL12795168 0.81 MAOA (0.49) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL22722495 0.80 ALDH1A1 (0.53) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL12795212 0.80 KDM4E (0.44) KDM4EALDH1A1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10442940-B2 Radiation curable compositions for food packaging AGFA NV (BE) 2019-10-15 US disclosed
US-10316204-B2 Radiation curable compositions for food packaging AGFA NV (BE) 2019-06-11 US disclosed
US-9796865-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2017-10-24 US disclosed
US-9796865-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2017-10-24 US disclosed
US-9718971-B2 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-01 US disclosed
US-9718971-B2 Curable liquids and inkjet inks for food packaging applications AGFA GRAPHICS NV (BE) 2017-08-01 US disclosed
US-9550898-B2 Radiation curable compositions for food packaging AGFA GRAPHICS NV (BE) 2017-01-24 US disclosed
US-9550898-B2 Radiation curable compositions for food packaging AGFA GRAPHICS NV (BE) 2017-01-24 US disclosed
US-9416287-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2016-08-16 US disclosed
US-9416287-B2 Curable liquids and inks for toys and food packaging applications AGFA GRAPHICS NV (BE) 2016-08-16 US disclosed
US-8133551-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BE) 2012-03-13 US disclosed
US-8133551-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BE) 2012-03-13 US disclosed
US-20110124768-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2011-05-26 US disclosed
US-20110124768-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2011-05-26 US disclosed
US-20100331478-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2010-12-30 US disclosed
US-20100331478-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2010-12-30 US disclosed
US-20100313782-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-16 US disclosed
US-20100313782-A1 CURABLE LIQUIDS AND INKS FOR TOYS AND FOOD PACKAGING APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-16 US disclosed
US-20100304149-A1 RADIATION CURABLE COMPOSITIONS FOR FOOD APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-02 US disclosed
US-20100304149-A1 RADIATION CURABLE COMPOSITIONS FOR FOOD APPLICATIONS AGFA GRAPHICS NV (BE) 2010-12-02 US disclosed