Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27888373 | 0.89 | ITGB1 (0.35) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL27888404 | 0.85 | ALDH1A1 (0.32) | MAPTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL2537624 | 0.84 | LMNA (0.46) | MAPTLMNAALDH1A1ALOX12MAPK1 | |
| SCHEMBL27888674 | 0.81 | LMNA (0.40) | MAPTLMNAALDH1A1ALOX12MAPK1 | |
| SCHEMBL27888360 | 0.79 | CYP19A1 (0.40) | MAPTLMNAALDH1A1KDM4EGAA | |
| SCHEMBL28803543 | 0.77 | SMN1; SMN2 (0.34) | MAPTLMNAALDH1A1KDM4EGAA | |
| SCHEMBL15509520 | 0.76 | KMT2A (0.36) | LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL27905167 | 0.76 | ALDH1A1 (0.36) | MAPTLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL1865349 | 0.75 | MAPT (0.61) | MAPTLMNAALDH1A1MAPK1RAF1 | |
| SCHEMBL27905174 | 0.73 | EPHX2 (0.41) | MAPTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858746-A | Novel 3,3-dimethyl tetrahydroquinoline derivatives | HOFFMANN LA ROCHE | 2013-01-02 | — | — | CN | disclosed |