Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781385 | 0.88 | KMT2A (0.46) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL18821943 | 0.85 | KMT2A (0.46) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL19186103 | 0.83 | RAB9A (0.47) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL27624527 | 0.83 | ACHE (0.58) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL20306078 | 0.82 | KMT2A (0.44) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL29111290 | 0.82 | SLC18A3 (0.57) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL26317202 | 0.81 | KMT2A (0.41) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL21726753 | 0.81 | KMT2A (0.43) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL25629349 | 0.81 | KMT2A (0.47) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 | |
| SCHEMBL25630177 | 0.81 | CHRNA7 (0.46) | KMT2AMEN1CHRNA7CHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712626-B | Piperazine compounds having PGDS inhibitory effect | TAIHO PHARMACEUTICAL CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-102712626-A | Piperazine compounds having PGDS inhibitory effect | TAIHO PHARMACEUTICAL CO LTD | 2012-10-03 | — | — | CN | disclosed |