Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890760 | 0.87 | P2RY6 (0.40) | P2RY6PTGS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27890732 | 0.86 | KCNQ3 (0.44) | P2RY6PTGS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27907532 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL27890786 | 0.75 | FABP3 (0.41) | P2RY6ALDH1A1KDM4ESMN1; SMN2FABP3 | |
| SCHEMBL27890734 | 0.75 | TP53 (0.47) | P2RY6PTGS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27890801 | 0.71 | MAPT (0.55) | PTGS1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL27890737 | 0.71 | KCNQ3 (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL27890739 | 0.69 | PTGS1 (0.47) | P2RY6PTGS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27907533 | 0.69 | PTGS1 (0.41) | P2RY6PTGS1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27797821 | 0.68 | PTGS1 (0.40) | P2RY6PTGS1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101906105-B | Pyrazolo (1,5-a) pyrimidone derivative as well as drug combination thereof and application thereof | UNIV HEBEI MEDICAL | 2013-01-16 | — | — | CN | disclosed |