Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907640 | 0.81 | FLT3 (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27890734 | 0.81 | TP53 (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13757487 | 0.81 | MEN1 (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27907529 | 0.81 | FUBP1 (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27890786 | 0.78 | FABP3 (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL28873587 | 0.77 | RPA1 (0.61) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL6457787 | 0.75 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL11391264 | 0.75 | RPA1 (0.67) | KDM4EALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL7995817 | 0.73 | MAPT (0.63) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6693299 | 0.72 | ATM (0.55) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101906105-B | Pyrazolo (1,5-a) pyrimidone derivative as well as drug combination thereof and application thereof | UNIV HEBEI MEDICAL | 2013-01-16 | — | — | CN | disclosed |