Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890747 | 0.82 | FLT3 (0.44) | MAPTALDH1A1GLAGAAKDM4E | |
| SCHEMBL27890801 | 0.78 | MAPT (0.55) | MAPTALDH1A1GLAGAAKDM4E | |
| SCHEMBL27890799 | 0.75 | P2RY6 (0.39) | FABP3MAPTTP53P2RY6ALDH1A1 | |
| SCHEMBL27890732 | 0.73 | KCNQ3 (0.44) | FABP3TP53P2RY6ALDH1A1KDM4E | |
| SCHEMBL27890734 | 0.71 | TP53 (0.47) | MAPTTP53P2RY6ALDH1A1KDM4E | |
| SCHEMBL8501358 | 0.69 | PGR (0.53) | MAPTALDH1A1GLAGAAKDM4E | |
| SCHEMBL27907533 | 0.68 | PTGS1 (0.41) | MAPTP2RY6ALDH1A1GAAKDM4E | |
| SCHEMBL27890739 | 0.68 | PTGS1 (0.47) | P2RY6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24049723 | 0.65 | PGR (0.56) | MAPTALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL19423220 | 0.65 | FABP3 (0.67) | FABP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101906105-B | Pyrazolo (1,5-a) pyrimidone derivative as well as drug combination thereof and application thereof | UNIV HEBEI MEDICAL | 2013-01-16 | — | — | CN | disclosed |