Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | PRKACG | P22612 | 1/20 | 0.41 |
| ▸ | PRKACB | P22694 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27939706 | 0.88 | MCL1 (0.52) | MCL1KDRSIGMAR1UTS2RSRC | |
| SCHEMBL27908745 | 0.86 | PGR (0.49) | MCL1UTS2RLMNAMEN1ALDH1A1 | |
| SCHEMBL27891760 | 0.85 | MCL1 (0.60) | MCL1UTS2RLMNAMEN1ALDH1A1 | |
| SCHEMBL27921185 | 0.84 | MCL1 (0.57) | MCL1KDRSIGMAR1SRCPRKACA | |
| SCHEMBL27891784 | 0.84 | MCL1 (0.57) | MCL1KDRSIGMAR1SRCPRKACA | |
| SCHEMBL31402856 | 0.82 | MCL1 (0.47) | MCL1KDRSIGMAR1UTS2RKLKB1 | |
| SCHEMBL31403142 | 0.80 | MCL1 (0.47) | MCL1KDRSIGMAR1UTS2RKLKB1 | |
| SCHEMBL31402863 | 0.80 | MCL1 (0.47) | MCL1KDRUTS2RKLKB1KLK1 | |
| SCHEMBL31402860 | 0.79 | MCL1 (0.43) | MCL1KDRSIGMAR1UTS2RSRC | |
| SCHEMBL27992186 | 0.79 | MCL1 (0.52) | MCL1KDRSIGMAR1SRCPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146080-B | Beta-carboline alkali derivative compounds and application thereof | XINJIANG HUASHIDAN PHARMACEUTICAL CO LTD | 2013-01-30 | — | — | CN | disclosed |