SCHEMBL27891778

SCHEMBL27891778

NOC(=O)C1(C(=O)ON)C=CC=CC1C=Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
LMNA P02545 4/20 0.36
KDM4E B2RXH2 3/20 0.36
POLB P06746 1/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 4/20 0.35
ADORA3 P0DMS8 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.35
XBP1 P17861 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM1A O60341 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HDAC3 O15379 1/20 0.33
TNKS O95271 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28221256 0.76 KDM1A (0.43) MAPTLMNAKDM4EPOLBHTT
SCHEMBL9227469 0.76 KDM1A (0.43) MAPTLMNAKDM4EPOLBHTT
SCHEMBL27994185 0.72 KDM4E (0.32) MAPTLMNAKDM4EPOLBHTT
SCHEMBL4636573 0.70 LMNA (0.33) MAPTLMNAKDM4EPOLBHTT
SCHEMBL31193007 0.70 MAPT (0.39) MAPTLMNAKDM4EPOLBHTT
SCHEMBL31193035 0.70 MAPT (0.39) MAPTLMNAKDM4EPOLBHTT
SCHEMBL599619 0.70 LMNA (0.38) MAPTLMNAKDM4EPOLBHTT
SCHEMBL27745443 0.70 KDM1A (0.41) MAPTLMNAKDM4EPOLBHTT
SCHEMBL5112549 0.70 KDM1A (0.41) MAPTLMNAKDM4EPOLBHTT
Ammonia Solution, Strong SCHEMBL27541097 0.69 LMNA (0.33) MAPTLMNAKDM4EPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102906239-A Optical brighteners and compositions comprising the same MILLIKEN & CO 2013-01-30 CN disclosed