SCHEMBL28221256

SCHEMBL28221256

NC1(N)C=CC=C[C@@H]1C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.43
MAOB P27338 3/20 0.37
CYP19A1 P11511 2/20 0.36
MAOA P21397 2/20 0.36
LMNA P02545 2/20 0.33
CHAT P28329 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9227469 1.00 KDM1A (0.43) KDM1AMAOBCYP19A1MAOALMNA
Diethanolamine SCHEMBL27326507 0.85 KDM1A (0.33) KDM1ALMNAKDM4EPOLBMAPT
SCHEMBL27745443 0.82 KDM1A (0.41) KDM1AMAOBCYP19A1MAOALMNA
SCHEMBL599619 0.82 LMNA (0.38) KDM1AMAOBLMNACHATKDM4E
SCHEMBL5112549 0.82 KDM1A (0.41) KDM1AMAOBCYP19A1MAOALMNA
SCHEMBL27844897 0.78 KDM1A (0.38) KDM1ALMNAKDM4EPOLBMAPT
SCHEMBL27891778 0.76 MAPT (0.36) KDM1ALMNAKDM4EPOLBMAPT
SCHEMBL31193007 0.76 MAPT (0.39) KDM1AMAOALMNAKDM4EPOLB
SCHEMBL31193035 0.76 MAPT (0.39) KDM1AMAOALMNAKDM4EPOLB
SCHEMBL4636573 0.76 LMNA (0.33) KDM1ALMNAKDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299833-A A kind of chirality polyShiff base cobalt salt composite wave-suction material 南昌航空大学 2018-07-20 CN claimed
CN-108299833-A A kind of chirality polyShiff base cobalt salt composite wave-suction material 南昌航空大学 2018-07-20 CN disclosed