Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180713 | 0.93 | PSIP1 (1.00) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| Fluoride SCHEMBL9493182 | 0.90 | PSIP1 (0.95) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| Ammonia Solution, Strong SCHEMBL6978426 | 0.90 | PSIP1 (0.95) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| Methylamine SCHEMBL28266275 | 0.88 | PSIP1 (0.90) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 | |
| Sulfuric Acid SCHEMBL27681094 | 0.86 | PSIP1 (0.86) | PSIP1ALDH1A1HSD17B10HSD11B1GAA | |
| Methylphenylsulfone SCHEMBL9733545 | 0.84 | PSIP1 (0.82) | PSIP1ALDH1A1HSD17B10HSD11B1GAA | |
| SCHEMBL14431973 | 0.84 | PSIP1 (0.82) | PSIP1ALDH1A1HSD17B10HSD11B1GAA | |
| SCHEMBL789569 | 0.84 | PSIP1 (0.82) | PSIP1ALDH1A1HSD17B10HSD11B1GAA | |
| Acetic Acid SCHEMBL28112958 | 0.84 | PSIP1 (0.82) | PSIP1ALDH1A1HSD17B10HSD11B1GAA | |
| Phenol SCHEMBL28291911 | 0.82 | PSIP1 (0.78) | PSIP1ALDH1A1HSD17B10TDP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130855-B | Succinylated hydroxy amine derivatives and application thereof | 约翰斯霍普金斯大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-105130855-A | Bis-Acylated Hydroxylamine Derivatives | UNIV JOHNS HOPKINS | 2015-12-09 | — | — | CN | disclosed |
| CN-102753519-B | Diacylated hydroxylamine derivatives | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-08-05 | — | — | CN | disclosed |
| CN-102753519-A | Diacylated hydroxylamine derivatives | UNIV JOHNS HOPKINS | 2012-10-24 | — | — | CN | disclosed |