Acetoacetic Acid

Acetoacetic Acid

SCHEMBL27893162

CC(=O)CC(=O)[O-].CC(=O)CC(=O)[O-].CCCCO[Zr+2]OCCCC

nearest known ligand 0.41

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
CA1 P00915 2/20 0.38
CES2 O00748 2/20 0.36
ATM Q13315 1/20 0.34
CES1 P23141 2/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.32
FFAR3 O14843 2/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
CA4 P22748 1/20 0.32
FAAH O00519 1/20 0.32
EPHX1 P07099 1/20 0.32
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL6064324 0.86 ALDH1A1 (0.48) ALDH1A1CA1CES2ATMCES1
SCHEMBL17105995 0.84 CA1 (0.36) ALDH1A1CA1CES2ATMCES1
SCHEMBL453162 0.82 CA1 (0.39) ALDH1A1CA1CES2ATMCES1
SCHEMBL17105987 0.82 CA1 (0.44) ALDH1A1CA1CES2ATMCES1
Butyric Acid SCHEMBL30339117 0.81 FFAR3 (0.56) ALDH1A1CA1CES2CES1FFAR3
SCHEMBL29408744 0.81 CA1 (0.38) ALDH1A1CA1CES2ATMCES1
SCHEMBL17106051 0.81 HAO1 (0.47) CA1CES2CES1
SCHEMBL17106079 0.80 HAO1 (0.50) CES2CES1
Methacrylic Acid SCHEMBL27657709 0.79 TSHR (0.43) ALDH1A1CA1CES2ATMCES1
Acetoacetic Acid SCHEMBL7213762 0.79 ALDH1A1 (0.42) ALDH1A1CA1CES2ATMCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115210295-A Fluorine-containing alcohol complex 优迈特株式会社 2022-10-18 CN disclosed
CN-102741048-B Water-repellent substrate and method for producing same ASAHI GLASS CO LTD 2014-09-03 CN disclosed
CN-102741048-A Water-repellent substrate and method for producing same ASAHI GLASS CO LTD 2012-10-17 CN disclosed