Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | PER2 | O15055 | 2/20 | 0.40 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.40 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792273 | 0.89 | CNR2 (0.44) | CNR2PER2CRY1CRY2PROKR1 | |
| SCHEMBL2790575 | 0.78 | DPP4 (0.37) | CNR2PER2CRY1CRY2PROKR1 | |
| SCHEMBL2792403 | 0.77 | PROKR1 (0.49) | CNR2PER2CRY1CRY2PROKR1 | |
| SCHEMBL2790515 | 0.77 | PROKR1 (0.37) | CNR2PROKR1ALDH1A1KDM4ETSHR | |
| SCHEMBL2792058 | 0.77 | CNR2 (0.48) | CNR2HTR4CYP3A4KCNH2ALDH1A1 | |
| SCHEMBL7900750 | 0.76 | TMEM97 (0.43) | — | |
| SCHEMBL739857 | 0.75 | HRH1 (0.57) | KCNH2 | |
| SCHEMBL2791354 | 0.73 | PROKR1 (0.37) | CNR2PROKR1ALDH1A1TSHRMEN1 | |
| SCHEMBL2789942 | 0.71 | PROKR1 (0.45) | CNR2PROKR1HTR4CYP3A4KCNH2 | |
| SCHEMBL2788091 | 0.70 | PROKR1 (0.42) | CNR2PROKR1HTR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |