Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | PER2 | O15055 | 1/20 | 0.42 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.42 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789345 | 0.89 | CNR2 (0.47) | CNR2PER2CRY1CRY2PROKR1 | |
| SCHEMBL2792403 | 0.89 | PROKR1 (0.49) | CNR2PER2CRY1CRY2HTR6 | |
| SCHEMBL2789961 | 0.80 | ALOX5AP (0.40) | HTR6BCHEACKR3SCN9AALOX5AP | |
| SCHEMBL2789214 | 0.79 | CNR2 (0.44) | CNR2HTR6BCHEACKR3SCN9A | |
| SCHEMBL7900706 | 0.79 | ALOX5AP (0.42) | HTR6BCHEACKR3SCN9AALOX5AP | |
| SCHEMBL2788969 | 0.79 | SCN9A (0.41) | CNR2SCN9APROKR1 | |
| SCHEMBL741975 | 0.78 | KCNH2 (0.52) | HPGDSCHRM1 | |
| SCHEMBL741974 | 0.78 | KCNH2 (0.52) | HPGDSCHRM1 | |
| SCHEMBL7901024 | 0.77 | ALOX5AP (0.41) | HTR6BCHEACKR3SCN9AALOX5AP | |
| SCHEMBL7902418 | 0.77 | LMNA (0.42) | HTR6BCHEACKR3ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |