Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 11/20 | 0.56 |
| ▸ | PLA2G10 | O15496 | 10/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.49 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.49 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.49 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.49 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.49 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.49 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17269936 | 0.87 | PLA2G2A (0.56) | PLA2G2APLA2G10SLCO1B1HNF4APLA2G1B | |
| SCHEMBL6129594 | 0.80 | PLA2G2A (0.56) | PLA2G2APLA2G10SLCO1B1HNF4APLA2G1B | |
| SCHEMBL31510727 | 0.79 | SRD5A2 (0.54) | PLA2G2APLA2G10DGAT1PARP15PARP10 | |
| SCHEMBL31413134 | 0.79 | DGAT1 (0.56) | DGAT1PARP15PARP10LMNAHTT | |
| SCHEMBL15729805 | 0.79 | DGAT1 (0.56) | DGAT1PARP15PARP10LMNAHTT | |
| SCHEMBL23387586 | 0.77 | DGAT1 (0.55) | DGAT1PARP15PARP10LMNAHTT | |
| Hydrochloric Acid SCHEMBL17091113 | 0.77 | DGAT1 (0.55) | DGAT1PARP15PARP10LMNAHTT | |
| SCHEMBL10211142 | 0.77 | DGAT1 (0.55) | DGAT1PARP15PARP10LMNAHTT | |
| SCHEMBL17315189 | 0.77 | DGAT1 (0.55) | DGAT1PARP15PARP10LMNAHTT | |
| SCHEMBL9937529 | 0.77 | HCAR2 (0.51) | HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102757426-A | Benzoisooxazolyl substituted thiazole compound, preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2012-10-31 | — | — | CN | disclosed |