Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895116 | 0.90 | PDK2 (0.44) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL27895118 | 0.89 | PDK2 (0.48) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL29351148 | 0.80 | PDK2 (0.54) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL17050236 | 0.80 | PDK2 (0.54) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL30211372 | 0.80 | PDK2 (0.54) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL194556 | 0.80 | PDK2 (0.54) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL27878248 | 0.78 | CA12 (0.48) | — | |
| SCHEMBL27878251 | 0.78 | PDK2 (0.49) | PDK2ALDH1A1ESR1ESR2KDM4E | |
| SCHEMBL21215204 | 0.78 | PDK2 (0.49) | PDK2ALDH1A1RECQLESR1ESR2 | |
| SCHEMBL20411195 | 0.77 | ALDH1A1 (0.55) | PDK2ALDH1A1RECQLESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102727470-A | Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer | UNIV BEIJING | 2012-10-17 | — | — | CN | disclosed |