Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095743 | 0.96 | GSR (0.38) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL16095744 | 0.96 | GSR (0.38) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL27919816 | 0.82 | CYP19A1 (0.40) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL18398614 | 0.81 | LMNA (0.33) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL28064432 | 0.81 | LMNA (0.33) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL27621632 | 0.81 | LMNA (0.33) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL21828117 | 0.79 | CHRM1 (0.46) | GSRNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL1766146 | 0.77 | BTK (0.33) | L3MBTL1SMN1; SMN2DPP4LMNA | |
| SCHEMBL16096263 | 0.77 | BTK (0.33) | L3MBTL1SMN1; SMN2DPP4LMNA | |
| SCHEMBL1766144 | 0.77 | BTK (0.33) | L3MBTL1SMN1; SMN2DPP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641889-A | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | 百欧伊米克思有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-103214414-A | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD | 2013-07-24 | — | — | CN | disclosed |
| CN-101263110-B | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-102753548-A | Fused heteroaromatic pyrrolidones as SYK inhibitors | TAKAEDA CHEMICAL IND LTD | 2012-10-24 | — | — | CN | disclosed |